Composition:

1 g of the veterinary medicinal product contains:

Active substance:
Doxycyclini hyclas 50.0 mg 

Excipients: Acidum citricum, Lactosum monohydricum.

Yellowish homogenous powder.

Indications:

It is effective against gram-negative and gram-positive bacteria susceptible to tetracyclines with the MICs lower than in other tetracycline antibiotics. It is intended for the treatment of secondary bacterial infections after viral diseases of target animal species
Chicken: CRD (Mycoplasma gallisepticum, Mycoplasma synoviae), colibacillosis (Escherichia coli).
Pigs: pneumonia (Actinobacillus pleuropneumoniae, Bordetella bronchiseptica, Mycoplasma hyopneumoniae and Pasteurella multocida), colibacillosis (Escherichia coli), MMA syndrome (Escherichia coli and Klebsiella pneumoniae).
Calf: pneumonia (Haemophilus spp., Mycoplasma hyorhinis), pasteurellosis (Pasteurella multocida), colibacillosis (Escherichia coli), salmonellosis (Salmonella spp.), pneumoenteritis, therapy of secondary infections after viral diseases.
Rabbits: pneumonia (Pasteurella multocida), colibacillosis (Escherichia coli). 

Dosage for each species, route and method of administration:

Pigs: 

10 mg active substance per kg bodyweight and day, i.e. 0.2 g of the veterinary medicinal product per 1 kg bodyweight or 2 g of the veterinary medicinal product per 1 litre of water, via drinking water or slurry feedstuff (first dissolve the product in water due to the moisturizing of the feed) for 5 days.
It is recommended to divide daily therapeutic dose into two halves.

Calves: 

7.5 mg active substance (0.15 g of the veterinary medicinal product) per 1 kg bodyweight and day for 5 days (1.5 g of the veterinary medicinal product per 10 kg bodyweight and day), dissolved in water.

Rabbits:

10 mg active substance (0.2 g of the veterinary medicinal product) per 1 kg of bodyweight and day for 5 days.

Poultry:

Administer via drinking water.

10 mg of doxycycline per kg bodyweight and day, i.e. 0.2 g of the veterinary medicinal product per kg bodyweight, for 4-5 consecutive days.
According to the recommended dose, the number and weight of treated animals, the exact daily dose of DOXYGAL 50 mg/g powder for oral solution, should be calculated using the following formula: 

(...g Doxygal 50 mg/g plv.sol. per kg bw. and day x Average bodyweight (kg) of treated animals)/ Average daily water consumption (L) per animal = ...g Doxygal 50 mg/g plv.sol. per 1 litre of drinking water

To ensure administration of correct dose, bodyweight should be determined as accurately as possible.
Medicated water intake depends on climate conditions. 
To ensure correct dosage the concentration has to be adjusted accordingly.
If separable bags are used, it is recommended to use suitable calibrated weights.
Preparation of daily dose of medicated water should provide an amount to be consumed within the next 2 hours.

Freshly medicated water for the next 2 hours should be prepared only. It is recommended to prepare concentrated preliminary solution – approximately 100 g of veterinary medicinal product per 1 litre of drinking water, which is, if applicable, subsequently diluted into therapeutic concentration. 

Route of administration:

Orally, dissolved in drinking water or individually incorporated into the feed. For immediate consumption after the incorporation into the feed. 

Withdrawal period:

Meat and offal:
Chicken and rabbits: 7 days.
Pig: 10 days.
Calves: 14 days.

Do not use in layers producing eggs for human consumption.

Contraindications:

Do not use in disorders of feed or beverages intake. Do not use in pregnant, lactating animals and during tooth development of young animals. Oral admnistration to adult cattle is not effective.

Adverse reactions:

Mild GIT problems (nausea, vomiting, diarrhoea, meteorism), hypovitaminosis B and K, damage and colouring of teeth, decreased growth of long bones. 

Special precautions for storage:

Keep out of the reach and sight of children.

Store at 25°C, in a dry place.
Protect from light.

Do not use this veterinary medicinal product after the expiry date which is stated on the label.
Shelf life after dilution according to directions: 24 hours.
Shelf life after incorporation into the feed: for immediate consumption.  

For more information please read the package leaflet.